Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior
نویسندگان
چکیده
منابع مشابه
Effects of cortical inactivation and stimulation on thalamic processing
The thalamus is the main sensory input to the cerebral cortex, not only for auditory stimuli, but also for visual and somatosensory stimuli (Alitto and Usrey, 2003). On the other hand, approximately half of the neuron input to the dorsal thalamus come from the cortex. These corticothalamic feedback connections seem to be important for sensory processing in the visual, auditory and somatosensory...
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Although spontaneous activity occurs throughout the neocortex, its relation to the activity produced by external or sensory inputs remains unclear. To address this, we used calcium imaging of mouse thalamocortical slices to reconstruct, with single-cell resolution, the spatiotemporal dynamics of activity of layer 4 in the presence or absence of thalamic stimulation. We found spontaneous neurona...
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Central thalamic deep brain stimulation (CT-DBS) has been proposed as an experimental therapeutic approach to produce consistent sustained regulation of forebrain arousal for several neurological diseases. We investigated local field potentials (LFPs) induced by CT-DBS from the thalamic central lateral nuclei (CL) and the striatum as potential biomarkers for the enhancement of lever-pressing sk...
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Studies on the visual thalamic relays, the lateral geniculate nucleus and pulvinar, provide three key properties that have dramatically changed the view that the thalamus serves as a simple relay to get information from subcortical sites to cortex. First, the retinal input, although a small minority (7%) in terms of numbers of synapses onto geniculate relay cells, dominates receptive field prop...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2020
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1370-20.2020